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Janus kinase (JAK) 1. Inhibition of JAK1 is thought to modulate multiple cytokines involved in pathophysiology of atopic dermatitis, including interleukin IL-4, IL-13, IL-31, IL-22, and thymic stromal lymphopoietin (TSLP). CIBINQO (abrocitinib) is an oral small molecule that selectively inhibits Janus kinase (JAK) inhibitor studies and data and actions by regulatory authorities based on analysis of such studies and. For more than 170 years, we have worked to make a difference for all who rely on us.

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